publications

주요실적

  1. 01Kim YE, Kim DH, Choi A, Jang S, Jeong K, Kim YM*, Nam TG*. (2021) Bi-aryl Analogues of Salicylic Acids: Design, Synthesis and SAR Study to Ameliorate Endoplasmic Reticulum Stress. Drug Des Devel Ther. 15:3593-3604. *corresponding author.

  2. 02Kim HY, Choi YJ, Kim SK, Kim H, Jun DW, Yoon K, Kim N, Hwang J, Kim YM, Lim SC, Kang KW. (2021) Auranofin prevents liver fibrosis by system Xc-mediated inhibition of NLRP3 inflammasome. Commun Biol. 4(1):824.

  3. 03An S, Kim G, Kim HJ, Ahn S, Kim HY, Ko H, Hyun YE, Nguyen M, Jeong J, Liu Z, Han J, Choi H, Yu J, Kim JW, Lee HW, Jacobson KA, Cho WJ, Kim YM, Kang KW, Noh M, Jeong LS. (2020) Discovery and Structure-Activity Relationships of Novel Template, Truncated 1'-Homologated Adenosine Derivatives as Pure Dual PPARγ/δ Modulators. J Med Chem. 63(24):16012-16027.

  4. 04Kim EK. Kim JH, Jeong S, Choi YW, Choi HJ, Kim CY*. Kim YM*. (2019) Pachypodol, a Methoxyflavonoid Isolated from Pogostemon cablin Bentham Exerts Antioxidant and Cytoprotective Effects in HepG2 Cells: Possible Role of ERK-Dependent Nrf2 Activation. Int J Mol Sci. 20(17). pii:E4082. *corresponding author.

  5. 05Yang HY, Kim KS, Lee YH, Park JH, Kim JH, Lee SY, Kim YM, Kim IS, Kacew S, Lee BM, Kwak JH, Yoon K, Kim HS. (2019) Dendropanax morbifera ameliorates thioacetamide-induced hepatic fibrosis via TGF-β1/Smads pathways. Int J Biol Sci. 15(4):800-811.

  6. 06Kim MI, Kim JH, Syed AS, Kim YM, Choe KK, Kim CY. (2018) Application of Centrifugal Partition Chromatography for Bioactivity-Guided Purification of Antioxidant-Response-Element-Inducing Constituents from Atractylodis Rhizoma Alba. Molecules. 23(9). pii: E2274.

  7. 07Kim KS, Yang HY, Chang SC, Kim YM, Lee KY, Lee BM, Kim HS. (2018) Potential repositioning of GV1001 as a therapeutic agent for testosterone-induced benign prostatic hyperplasia. Int J Mol Med. 42(4):2260-2268.

  8. 08Kim JS, Son JY, Kim KS, Lim HJ, Ahn MY, Kwack SJ, Kim YM, Lee KY, Lee J, Lee BM, Kim HS. (2018) Hepatic damage exacerbates cisplatin-induced acute kidney injury in Sprague-Dawley rats. J Toxicol Environ Health A. 81(11):397-407.

  9. 09Yang JW, Kim HS, Choi YW, Kim YM*, Kang KW*. (2018) Therapeutic application of GPR119 ligands in metabolic disorders. Diabetes Obes Metab. 20:257-269. *corresponding author.

  10. 10Jeon JS, Oh JJ, Kwak HC, Yun HY, Kim HC, Kim YM, Oh SJ, Kim SK. (2018) Age-Related Changes in Sulfur Amino Acid Metabolism in Male C57bl/6 Mice. Biomol Ther (Seoul). 26:167-174.

  11. 11Han Y, Kim YM, Kim HS, Lee KY. (2017) Melatonin promotes osteoblast differentiation by regulating Osterix protein stability and expression. Sci Rep. 7:5716.

  12. 12Kim KS, Yang HY, Song H, Kang YR, Kwon J, An J, Son JY, Kwack SJ, Kim YM, Bae ON, Ahn MY, Lee J, Yoon S, Lee BM, Kim HS. (2017) Identification of a sensitive urinary biomarker, selenium-binding protein 1, for early detection of acute kidney injury. J Toxicol Environ Health A. 80:453-464.

  13. 13Seo Y, Song JS, Kim YM*, Jang YP*. (2017) Toralactone glycoside in Cassia obtusifolia mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism. Food Res Int. 97:340-346. *corresponding author.

  14. 14Bui QT, Lim JH, Jeong SB, Kim YM, Lim SC, Kim B, Kang KW. (2017) Essential role of Notch4/STAT3 signaling in epithelial-mesenchymal transition of tamoxifen-resistant human breast cancer. Cancer Lett. 390:115-125.

  15. 15Song JS, Kim EK, Choi YW, Oh WK, Kim YM. (2016) Hepatocyte-protective effect of nectandrin B, a nutmeg lignan, against oxidative stress: Role of Nrf2 activation through ERK phosphorylation and AMPK-dependent inhibition of GSK-3β. Toxicol. Appl. Pharmacol. 307:138-149.

  16. 16Phuong NT, Kim SK, Im JH, Yang JW, Choi MC, Lim SC, Lee KY, Kim YM, Yoon JH, Kang KW. (2016) Induction of methionine adenosyltransferase 2A in tamoxifen-resistant breast cancer cells. Oncotarget. 7:13902-13916.

  17. 17Jeon JS, Park CL, Syed AS, Kim YM, Cho IJ, Kim CY. (2016) Preparative separation of sesamin and sesamolin from defatted sesame meal via centrifugal partition chromatography with consecutive sample injection. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 1011:108-113.

  18. 18Choi DG, Kim EK, Yang JW, Song JS, Kim YM. (2015) Nectandrin B, a lignan isolated from nutmeg, inhibits liver X receptor-α-induced hepatic lipogenesis through AMP-activated protein kinase activation. Pharmazie. 70:733-739.

  19. 19Kwak HC, Kim YM, Oh SJ, Kim SK. (2015) Sulfur amino acid metabolism in Zucker diabetic fatty rats. Biochem. Pharmacol. 96:256-266.

  20. 20Choi JM, Oh SJ, Lee JY, Jeon JS, Ryu CS, Kim YM, Lee K, Kim SK. (2015) Prediction of drug-induced liver injury in HepG2 cells cultured with human liver microsomes. Chem. Res. Toxicol. 8:872-885.

  21. 21Lee SY, Lee JY, Kim YM, Kim SK, Oh SJ. (2015) Expression of hepatic cytochrome P450s and UDP-glucuronosyltransferases in PXR and CAR double humanized mice treated with rifampicin. Toxicol. Lett. 235:107-115.

  22. 22Phuong NT, Lim SC, Kim YM, Kang KW. (2014) Aromatase induction in tamoxifen-resistant breast cancer: Role of phosphoinositide 3-kinase-dependent CREB activation. Cancer Lett. 351:91-99.

  23. 23Choi YJ, Kim YM, Chung JY, Cho JY, Yu KS, Jang IJ, Lim KS. (2013) A randomized, open label, 2-way crossover study to assess the pharmacokinetic characteristics and skin irritation of Murupe® patch compared with Trast® patch in healthy volunteers. J. Korean Soc. Clin. Pharmacol. Ther. 21:41-51.

  24. 24Kim YM, Park TS, Kim SG. (2013) The role of sphingolipids in drug metabolism and transport. Expert Opin. Drug Metab. Toxicol. 9:319-331.

  25. 25Lee MH, Kim YM, Kim SG. (2012) Efficacy and tolerability of diphenyl-dimethyldicarboxylate plus garlic oil in patients with chronic hepatitis. Int. J. Clin. Pharmacol. Ther. 50:778-786.

  26. 26Noh K*, Kim YM*, Kim YW, Kim SG. (2011) FXR activation by chenodeoxycholic acid induces detoxifying enzymes through AMPK and ERK1/2-mediated phosphorylation of CCAAT/enhancer binding protein β. Drug Metab. Dispos. 39:1451-1459. *equal contribution

  27. 27Kim SG*, Kim YM*, Choi JY, Han JY, Jang JW, Cho SH, Um SH, Chon CY, Lee DH, Jang JJ, Yu E, Lee YS. (2011) Oltipraz therapy in patients with liver fibrosis or cirrhosis: a randomized, double-blind, placebo-controlled phase II trial. J. Pharm. Pharmacol. 63:627-635. *equal contribution

  28. 28Kim YM, Lim SC, Han CY, Kay HY, Cho IJ, Ki SH, Lee MY, Kwon HM, Lee CH, Kim SG. (2011) Galpha12/13 induction of CYR61 in association with arteriosclerotic intimal hyperplasia: effect of sphingosine-1-phosphate. Arterioscler. Thromb. Vasc. Biol. 31:861-869.

  29. 29Kim YM*, Kim TH*, Kim YW, Yang YM, Ryu da H, Hwang SJ, Lee JR, Kim SC, Kim SG. (2010) Inhibition of liver X receptor-α-dependent hepatic steatosis by isoliquiritigenin, a licorice antioxidant flavonoid, as mediated by JNK1 inhibition. Free Radic. Biol. Med. 49:1722-1734. *equal contribution

  30. 30Kim SG*, Kim YM*, Choi YH, Lee MG, Choi JY, Han JY, Cho SH, Jang JW, Um SH, Chon CY, Lee DH, Jang JJ, Yu ES, Lee YS. (2010) Pharmacokinetics of oltipraz and its major metabolite (RM) in patients with liver fibrosis or cirrhosis: relationship with suppression of circulating TGF-beta1. Clin. Pharmacol. Ther. 88:360-368. *equal contribution.

  31. 31Lee SJ, Lee WH, Ki SH, Kim YM, Lee SJ, Lee CH, Kim SG. (2009) Galpha13 regulates methacholine-induced contraction of bronchial smooth muscle via phosphorylation of MLC20. Biochem. Pharmacol. 77:1497-1505.

  32. 32Ah YM, Kim YM, Kim MJ, Choi YH, Park KH, Son IJ, Kim SG. (2008) Drug-induced hyperbilirubinemia and the clinical influencing factors. Drug Metab. Rev. 40:511-537.

  33. 33Kim YM, Yoo SH, Kang RY, Kim MJ, Bae YY, Lee YK, Jeon SJ, Chon KJ, Shin SM, Kim SG, Park KH, Son IJ. (2007) Identifying drugs needing pharmacogenetic monitoring in a Korean hospital. Am. J. Health Syst. Pharm. 64:166-175.

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