주요실적
1.
Kang KM, Han JH, Kim KS,
Kim EK, Shin Y, Park JH, Kim H, Kim NY, Kim YG, Kim H, Park H, Kim YM, Kee SJ,
Kim SJ, Kim HS, Kim YC. (2024) Chlorophyll a and novel synthetic derivatives
alleviate atopic dermatitis by suppressing Th2 cell differentiation via IL-4
receptor modulation. Clin Immunol. 258:109852.
2.
Kim HY, Undarmaa
Otgontenger, Kim JW, Lee YJ, Kim SB, Lim SC, Kim YM*, Kang KW*. (2023)
Anti-fibrotic effect of aurocyanide, the active metabolite of auranofin. Arch
Pharm Res. 46(3):149-159. *corresponding author
3.
Park M, Lee SH, Bui QT,
Kim YM*, Kang KW*. (2022) The essential role of YAP in ERα36-mediated
proliferation and the epithelial-mesenchymal transition in MCF-7 breast cancer
cells. Front Pharmacol. 13:1057276. *corresponding author
4.
Kim YE, Kim DH, Choi A, Jang S, Jeong K,
Kim YM*, Nam TG*. (2021) Bi-aryl Analogues of Salicylic Acids: Design,
Synthesis and SAR Study to Ameliorate Endoplasmic Reticulum Stress. Drug Des
Devel Ther. 15:3593-3604. *corresponding author.
5.
Kim HY, Choi YJ, Kim SK, Kim H, Jun DW,
Yoon K, Kim N, Hwang J, Kim YM, Lim SC, Kang KW. (2021) Auranofin prevents
liver fibrosis by system Xc-mediated inhibition of NLRP3 inflammasome. Commun
Biol. 4(1):824.
6.
An S, Kim G, Kim HJ, Ahn S, Kim HY, Ko
H, Hyun YE, Nguyen M, Jeong J, Liu Z, Han J, Choi H, Yu J, Kim JW, Lee HW,
Jacobson KA, Cho WJ, Kim YM, Kang KW, Noh M, Jeong LS. (2020) Discovery and
Structure-Activity Relationships of Novel Template, Truncated 1'-Homologated
Adenosine Derivatives as Pure Dual PPARγ/δ Modulators. J Med Chem.
63(24):16012-16027.
7.
Kim EK. Kim JH, Jeong S, Choi YW, Choi
HJ, Kim CY*. Kim YM*. (2019) Pachypodol, a Methoxyflavonoid Isolated from
Pogostemon cablin Bentham Exerts Antioxidant and Cytoprotective Effects in
HepG2 Cells: Possible Role of ERK-Dependent Nrf2 Activation. Int J Mol Sci.
20(17). pii:E4082. *corresponding author.
8.
Yang HY, Kim KS, Lee YH, Park JH, Kim
JH, Lee SY, Kim YM, Kim IS, Kacew S, Lee BM, Kwak JH, Yoon K, Kim HS. (2019)
Dendropanax morbifera ameliorates thioacetamide-induced hepatic fibrosis via
TGF-β1/Smads pathways. Int J Biol Sci. 15(4):800-811.
9.
Kim MI, Kim JH, Syed AS, Kim YM, Choe
KK, Kim CY. (2018) Application of Centrifugal Partition Chromatography for
Bioactivity-Guided Purification of Antioxidant-Response-Element-Inducing
Constituents from Atractylodis Rhizoma Alba. Molecules. 23(9). pii: E2274.
10. Kim KS, Yang HY,
Chang SC, Kim YM, Lee KY, Lee BM, Kim HS. (2018) Potential repositioning of
GV1001 as a therapeutic agent for testosterone-induced benign prostatic hyperplasia.
Int J Mol Med. 42(4):2260-2268.
11. Kim JS, Son JY,
Kim KS, Lim HJ, Ahn MY, Kwack SJ, Kim YM, Lee KY, Lee J, Lee BM, Kim HS. (2018)
Hepatic damage exacerbates cisplatin-induced acute kidney injury in
Sprague-Dawley rats. J Toxicol Environ Health A. 81(11):397-407.
12. Yang JW, Kim HS,
Choi YW, Kim YM*, Kang KW*. (2018) Therapeutic application of GPR119 ligands in
metabolic disorders. Diabetes Obes Metab. 20:257-269. *corresponding author.
13. Jeon JS, Oh JJ,
Kwak HC, Yun HY, Kim HC, Kim YM, Oh SJ, Kim SK. (2018) Age-Related Changes in
Sulfur Amino Acid Metabolism in Male C57bl/6 Mice. Biomol Ther (Seoul).
26:167-174.
14. Han Y, Kim YM,
Kim HS, Lee KY. (2017) Melatonin promotes osteoblast differentiation by
regulating Osterix protein stability and expression. Sci Rep. 7:5716.
15. Kim KS, Yang HY,
Song H, Kang YR, Kwon J, An J, Son JY, Kwack SJ, Kim YM, Bae ON, Ahn MY, Lee J,
Yoon S, Lee BM, Kim HS. (2017) Identification of a sensitive urinary biomarker,
selenium-binding protein 1, for early detection of acute kidney injury. J
Toxicol Environ Health A. 80:453-464.
16. Seo Y, Song JS,
Kim YM*, Jang YP*. (2017) Toralactone glycoside in Cassia obtusifolia mediates
hepatoprotection via an Nrf2-dependent anti-oxidative mechanism. Food Res Int.
97:340-346. *corresponding author.
17. Bui QT, Lim JH,
Jeong SB, Kim YM, Lim SC, Kim B, Kang KW. (2017) Essential role of Notch4/STAT3
signaling in epithelial-mesenchymal transition of tamoxifen-resistant human
breast cancer. Cancer Lett. 390:115-125.
18. Song JS, Kim EK,
Choi YW, Oh WK, Kim YM. (2016) Hepatocyte-protective effect of nectandrin B, a
nutmeg lignan, against oxidative stress: Role of Nrf2 activation through ERK
phosphorylation and AMPK-dependent inhibition of GSK-3β. Toxicol. Appl.
Pharmacol. 307:138-149.
19. Phuong NT, Kim
SK, Im JH, Yang JW, Choi MC, Lim SC, Lee KY, Kim YM, Yoon JH, Kang KW. (2016)
Induction of methionine adenosyltransferase 2A in tamoxifen-resistant breast
cancer cells. Oncotarget. 7:13902-13916.
20. Jeon JS, Park
CL, Syed AS, Kim YM, Cho IJ, Kim CY. (2016) Preparative separation of sesamin
and sesamolin from defatted sesame meal via centrifugal partition
chromatography with consecutive sample injection. J. Chromatogr. B. Analyt.
Technol. Biomed. Life Sci. 1011:108-113.
21. Choi DG, Kim EK,
Yang JW, Song JS, Kim YM. (2015) Nectandrin B, a lignan isolated from nutmeg,
inhibits liver X receptor-α-induced hepatic lipogenesis through AMP-activated
protein kinase activation. Pharmazie. 70:733-739.
22. Kwak HC, Kim YM,
Oh SJ, Kim SK. (2015) Sulfur amino acid metabolism in Zucker diabetic fatty
rats. Biochem. Pharmacol. 96:256-266.
23. Choi JM, Oh SJ,
Lee JY, Jeon JS, Ryu CS, Kim YM, Lee K, Kim SK. (2015) Prediction of
drug-induced liver injury in HepG2 cells cultured with human liver microsomes.
Chem. Res. Toxicol. 8:872-885.
24. Lee SY, Lee JY,
Kim YM, Kim SK, Oh SJ. (2015) Expression of hepatic cytochrome P450s and
UDP-glucuronosyltransferases in PXR and CAR double humanized mice treated with
rifampicin. Toxicol. Lett. 235:107-115.
25. Phuong NT, Lim
SC, Kim YM, Kang KW. (2014) Aromatase induction in tamoxifen-resistant breast
cancer: Role of phosphoinositide 3-kinase-dependent CREB activation. Cancer
Lett. 351:91-99.
26. Choi YJ, Kim YM,
Chung JY, Cho JY, Yu KS, Jang IJ, Lim KS. (2013) A randomized, open label,
2-way crossover study to assess the pharmacokinetic characteristics and skin
irritation of Murupe® patch compared with Trast® patch in healthy volunteers.
J. Korean Soc. Clin. Pharmacol. Ther. 21:41-51.
27. Kim YM, Park TS,
Kim SG. (2013) The role of sphingolipids in drug metabolism and transport.
Expert Opin. Drug Metab. Toxicol. 9:319-331.
28. Lee MH, Kim YM,
Kim SG. (2012) Efficacy and tolerability of diphenyl-dimethyldicarboxylate plus
garlic oil in patients with chronic hepatitis. Int. J. Clin. Pharmacol. Ther.
50:778-786.
29. Noh K*, Kim YM*,
Kim YW, Kim SG. (2011) FXR activation by chenodeoxycholic acid induces
detoxifying enzymes through AMPK and ERK1/2-mediated phosphorylation of
CCAAT/enhancer binding protein β. Drug Metab. Dispos. 39:1451-1459. *equal
contribution
30. Kim SG*, Kim
YM*, Choi JY, Han JY, Jang JW, Cho SH, Um SH, Chon CY, Lee DH, Jang JJ, Yu E,
Lee YS. (2011) Oltipraz therapy in patients with liver fibrosis or cirrhosis: a
randomized, double-blind, placebo-controlled phase II trial. J. Pharm.
Pharmacol. 63:627-635. *equal contribution
31. Kim YM, Lim SC,
Han CY, Kay HY, Cho IJ, Ki SH, Lee MY, Kwon HM, Lee CH, Kim SG. (2011)
Galpha12/13 induction of CYR61 in association with arteriosclerotic intimal
hyperplasia: effect of sphingosine-1-phosphate. Arterioscler. Thromb. Vasc.
Biol. 31:861-869.
32. Kim YM*, Kim
TH*, Kim YW, Yang YM, Ryu da H, Hwang SJ, Lee JR, Kim SC, Kim SG. (2010)
Inhibition of liver X receptor-α-dependent hepatic steatosis by
isoliquiritigenin, a licorice antioxidant flavonoid, as mediated by JNK1
inhibition. Free Radic. Biol. Med. 49:1722-1734. *equal contribution
33. Kim SG*, Kim
YM*, Choi YH, Lee MG, Choi JY, Han JY, Cho SH, Jang JW, Um SH, Chon CY, Lee DH,
Jang JJ, Yu ES, Lee YS. (2010) Pharmacokinetics of oltipraz and its major
metabolite (RM) in patients with liver fibrosis or cirrhosis: relationship with
suppression of circulating TGF-beta1. Clin. Pharmacol. Ther. 88:360-368. *equal
contribution.
34. Lee SJ, Lee WH,
Ki SH, Kim YM, Lee SJ, Lee CH, Kim SG. (2009) Galpha13 regulates
methacholine-induced contraction of bronchial smooth muscle via phosphorylation
of MLC20. Biochem. Pharmacol. 77:1497-1505.
35. Ah YM, Kim YM,
Kim MJ, Choi YH, Park KH, Son IJ, Kim SG. (2008) Drug-induced
hyperbilirubinemia and the clinical influencing factors. Drug Metab. Rev.
40:511-537.
36. Kim YM, Yoo SH,
Kang RY, Kim MJ, Bae YY, Lee YK, Jeon SJ, Chon KJ, Shin SM, Kim SG, Park KH,
Son IJ. (2007) Identifying drugs needing pharmacogenetic monitoring in a Korean
hospital. Am. J. Health Syst. Pharm. 64:166-175.